In the Shadow of the Accretion Disk: Higher Resolution Imaging of the Central Parsec in NGC 4261

The physical conditions in the inner parsec of accretion disks believed to orbit the central black holes in active galactic nuclei can be probed by imaging the absorption (by ionized gas in the disk) of background emission from a radio counterjet. We report high angular resolution VLBI observations of the nearby (about 40 Mpc) radio galaxy NGC 4261 that confirm free-free absorption of radio emission from a counterjet by a geometrically thin, nearly edge-on disk at 1.6, 4.8, and 8.4 GHz. The angular width and depth of the absorption appears to increase with decreasing frequency, as expected. We derive an average electron density of ~10E4 per cc at a disk radius of about 0.2 pc, assuming that the inner disk inclination and opening angles are the same as at larger radii. Pressure balance between the thermal gas and the magnetic field in the disk implies an average field strength of 0.1 milligauss at a radius of 0.2 pc. These are the closest-in free-free absorption measurements to date of the conditions in an extragalactic accretion disk orbiting a black hole with a well-determined mass. If a standard advection-dominated accretion flow exists in the disk center, then the transition between thin and thick disk regions must occur at a radius less than 0.2 pc (4000 Schwarzschild radii).Comment: 20 pages including 12 figures. Accepted for publication in Ap

Implementation and evaluation of a transit dosimetry system for treatment verification

PURPOSE: To evaluate a formalism for transit dosimetry using a phantom study and prospectively evaluate the protocol on a patient population undergoing 3D conformal radiotherapy. METHODS: Amorphous silicon EPIDs were calibrated for dose and used to acquire images of delivered fields. The measured EPID dose map was back-projected using the planning CT images to calculate dose at pre-specified points within the patient using commercially available software, EPIgray (DOSIsoft, France). This software compared computed back-projected dose with treatment planning system dose. A series of tests were performed on solid water phantoms (linearity, field size effects, off-axis effects). 37 patients were enrolled in the prospective study. RESULTS: The EPID dose response was stable and linear with dose. For all tested field sizes the agreement was good between EPID-derived and treatment planning system dose in the central axis, with performance stability up to a measured depth of 18cm (agreement within -0.5% at 10cm depth on the central axis and within -1.4% at 2cm off-axis). 126 transit images were analysed of 37 3D-conformal patients. Patient results demonstrated the potential of EPIgray with 91% of all delivered fields achieved the initial set tolerance level of ΔD of 0±5-cGy or %ΔD of 0±5%. CONCLUSIONS: The in vivo dose verification method was simple to implement, with very few commissioning measurements needed. The system required no extra dose to the patient, and importantly was able to detect patient position errors that impacted on dose delivery in two of cases

Are GPs under-investigating older patients presenting with symptoms of ovarian cancer? Observational study using General Practice Research Database

Background: Recent studies suggest that older patients in the United Kingdom are not benefiting as much from improvements in cancer treatments as their younger counterparts. We investigate whether this might be partly due to differential referral rates using ovarian cancer as an example. Methods: From the General Practice Research Database (GPRD), we identified all women aged 40–80 years on 1 June 2002 with a Read code for ovarian cancer between 1 June 2002 and 31 May 2007. Using these records, we compared the GPRD incidence of ovarian cancer with rates compiled from the UK cancer registries and investigated the relationship between age and coded investigations for suspected ovarian cancer. Results: The GPRD rates peaked earlier, at 70–74, and were lower than registry rates for nearly all ages particularly for patients over 59. The proportion investigated or referred by the GP decreased significantly with age and delays between first coded symptom and investigation showed a U-shaped distribution by age. Conclusions: GPs appear to be less likely to recognise and to refer patients presenting with ovarian cancer as they get older. If our findings extend to other cancers, lack of or delays in referral to secondary care may partly explain poor UK cancer mortality rates of older people

The celebrity entrepreneur on television: profile, politics and power

This article examines the rise of the ‘celebrity entrepreneur’ on television through the emergence of the ‘business entertainment format’ and considers the ways in which regular television exposure can be converted into political influence. Within television studies there has been a preoccupation in recent years with how lifestyle and reality formats work to transform ‘ordinary’ people into celebrities. As a result, the contribution of vocationally skilled business professionals to factual entertainment programming has gone almost unnoticed. This article draws on interviews with key media industry professionals and begins by looking at the construction of entrepreneurs as different types of television personalities and how discourses of work, skill and knowledge function in business shows. It then outlines how entrepreneurs can utilize their newly acquired televisual skills to cultivate a wider media profile and secure various forms of political access and influence. Integral to this is the centrality of public relations and media management agencies in shaping media discourses and developing the individual as a ‘brand identity’ that can be used to endorse a range of products or ideas. This has led to policy makers and politicians attempting to mobilize the media profile of celebrity entrepreneurs to reach out and connect with the public on business and enterprise-related issues

The role of seagrass vegetation and local environmental conditions in shaping benthic bacterial and macroinvertebrate communities in a tropical coastal lagoon

We investigated the influence of seagrass canopies on the benthic biodiversity of bacteria and macroinvertebrates in a Red Sea tropical lagoon. Changes in abundance, number of taxa and assemblage structure were analyzed in response to seagrass densities (low, SLD; high, SHD; seagrasses with algae, SA), and compared with unvegetated sediments. Biological and environmental variables were examined in these four habitats (hereafter called treatments), both in the underlaying sediments and overlaying waters, at three randomly picked locations in March 2017. Differences between treatments were more apparent in the benthic habitat than in the overlaying waters. The presence of vegetation (more than its cover) and changes in sedimentary features (grain size and metals) at local scales influenced the observed biological patterns, particularly for macroinvertebrates. Of note, the highest percentage of exclusive macroinvertebrate taxa (18% of the gamma diversity) was observed in the SHD treatment peaking in the SA for bacteria. Benthic macroinvertebrates and bacteria shared a generally low number of taxa across treatments and locations; approximately, 25% of the gamma diversity was shared among all treatments and locations for macrofauna, dropping to 11% for bacteria. Given the low overlap in the species distribution across the lagoon, sustaining the connectivity among heterogeneous soft sediment habitats appears to be essential for maintaining regional biodiversity. This study addresses a current scientific gap related to the relative contributions of vegetated and unvegetated habitats to biodiversity in tropical regions.Peer reviewe

Assessment and treatment of distorted schemas in sexual offenders

The aim of this review is to examine the literature related to the assessment and treatment of sex offenders’ distorted schemas. Where appropriate, the review draws upon current insights from the field of social cognition to aid in the critical evaluation of the findings. First, the review considers the various different methodologies for assessing distorted schemas, discussing their strengths and limitations. Second, the review examines the work related to the treatment of sex offenders’ schemas. Suggestions for future research, and the implications for clinical practice, are highlighted in the article

The Origin of the Cosmic Soft X-Ray Background: Optical Identification of an Extremely Deep ROSAT Survey

We present the results of the deepest optically identified X-ray survey yet made. The X-ray survey was made with the ROSAT PSPC and reaches a flux limit of 1.6x10^-15 erg cm^-2 s^-1 (0.5--2.0 keV). Above a flux limit of 2x10^-15 erg cm^-2 s^-1 we define a complete sample of 70 sources of which 59 are identified. Some (5) other sources have tentative identifications and in a further 4 the X-ray error-boxes are blank to R=23 mag. At the brighter flux levels (>= 10^-14 erg cm^-2 s^-1) we confirm the results of previous less deep X-ray surveys with 84% of the sources begin QSOs. At fainter fluxes, however, the survey is dominated by a population of galaxies with narrow optical emission lines (NELGs). In addition, a number of groups and clusters of galaxies are found at intermediate fluxes. Most of these are poor systems of low X-ray luminosity and are generally found at redshifts of > 0.3. Their numbers are consistent with a zero evolutionary scenario, in contrast to the situation for high luminosity clusters at the same redshift. We discuss the significance of these results to the determination of the cosmic soft X-ray background (XRB) and show that at 2x10^-15 erg cm^-2 s^-1, we have resolved more than 50% of the background. We also briefly consider the probable importance of NELG objects to the residual background and look at some of the properties of these unusual objects.Comment: 28 pages, LaTeX, 17 figures from 32 postscript files. Uses mn.sty and epsf.sty. Accepted by MNRAS. Revised version now contains data table. For more information see http://www.astro.soton.ac.uk/~amn/UKdee

Coexisting conical bipolar and equatorial outflows from a high-mass protostar

The BN/KL region in the Orion molecular cloud is an archetype in the study of the formation of stars much more massive than the Sun. This region contains luminous young stars and protostars, but it is difficult to study because of overlying dust and gas. Our basic expectations are shaped to some extent by the present theoretical picture of star formation, the cornerstone of which is that protostars acrete gas from rotating equatorial disks, and shed angular momentum by ejecting gas in bipolar outflows. The main source of the outflow in the BN/KL region may be an object known as radio source I, which is commonly believed to be surrounded by a rotating disk of molecular material. Here we report high-resolution observations of silicon monoxide (SiO) and water maser emission from the gas surrounding source I; we show that within 60 AU (about the size of the Solar System), the region is dominated by a conical bipolar outflow, rather than the expected disk. A slower outflow, close to the equatorial plane of the protostellar system, extends to radii of 1,000 AU.Comment: 10 pages, 2 figures. Accepted by Nature. To appear December 199

Physical activity and mental health in women with polycystic ovary syndrome.

Physical activity is prescribed as a component of primary management for Polycystic Ovary Syndrome (PCOS). This study investigates the association between physical activity and mental health as well as the exercise barriers, motivators and support providers for younger women with and without PCOS to assist in physical activity uptake and prescription for these women